From Los Angeles International Airport(LAX):

Start out going Southeast on ramp
Merge onto S Sepulveda Blvd/CA-1 S
Take the I-105 E/Iperial Hwy West ramp toward Iperial Blvd
Merge onto I-105 E toward Norwalk
Merge onto I-110 N toward Los Angeles
I-110 N becomes CA-110 N.
Take the US-101 N exit toward Hollywood/I-5 S/Santa Ana/I-10 E/San Bernardino
Take the exit toward I-10/San Bernardino /I-5/Santa Ana
Take the Temple St exit
Turn right onto W Temple St
Turn right onto ramp
Turn right onto N Figueroa St
Turn left onto W Senset Blvd.

From John Wayne Airport-Orange County (SNA):

Take CA 55 Fwy N.
Merge onto I-5 N toward Los Angeles
Merge onto US-101 N via the exit on the left toward los Angeles/Civic Center
Take the CA-110/Pasadena Fwy/Grand Ave exit toward Harbor Fwy/San Pedro/Pasadena.
Take the Grand AVE exit
Turn right onto N Gand Ave
Turn right onto W TEMPLE
Turn right onto ramp
Turn slight right onto N Figueroa
Turn left onto W Sunset Blvd